According to the biology of addiction, scientists, studying it, in order to find out the best methods and methods of treatment to combat alcohol dependence, found that Tideglusib- which was originally developed for the treatment of Alzheimer, is effective in the fight against alcoholism.
Experiments conducted by scientists on experimental mice at the preclinical stage of testing for treatment showed that the drug significantly reduced the intake of chronic alcohol and excessive seizures of alcohol (alcohol consumption), especially for men in experimental animals, and no side effects were recorded when used for treatment of alcohol dependence.
The drug works, inhibiting protein activity, known as (GSK3β), its previous increase was associated with an increase in the desire to drink alcohol, and scientists suggest that the curbing of this protein can weaken the nerve circles responsible for the formation of alcoholism.
Alcohol dependence is still one of the main causes of prevention, which can be prevented around the world, and drugs that are currently available to treat this dependence are not suitable for (Nalterxon, Aquambrosate, Discs) with all patients, so the new discovery can open promising horizons for the treatment of this problem.
Researchers argue that the TIDEGLUSIB function is that it is already undergoing clinical trials for the treatment of other diseases, which can accelerate its adoption and future use for the treatment of dependence disorders.
Source: Linta.u
