Hydrophobia has nothing to do with irrational fear of water. In cases rageSomewhat more cruel: muscle contraction in the throat that prevents swallowing. The body is trying, but it cannot. The liquid came out and virus It accumulates inside. Thus, saliva becomes an ideal trap loaded with pathogens. The goal is clear: find another guest. In 1885, this threat He found a response in the laboratory in ParisField
The decision on interference was made after the desperate arrival of the mother from the asia
Nothing guaranteed success. Louis Pasteur He was not a doctor and was not authorized to treat patients. Despite this, he agreed to take part in a decision that no scientist in his environment supported. He did it at the request Jacques Joseph Greiter, A pediatrician and a tuberculosis expert who worked with him in the study of rabies. It was a granter who proposed, execution and controlled The human application of the vaccine, which was tested only in animalsLife field The child is bitten by a dog in Alsace This was left on an indefinite experiment.
This child was called Joseph Meister. I was nine years old and I got 14 bitesThe field is his mother, Marie-agelik, He went to Paris, hearing about a scientist who was developing treatment for rage. On July 6, 1885, Pasteur decided to act. The treatment consisted of Twelve doses are used for ten daysNone of his employees gave his approval by the field, and there was no clear legal basis for intervention.
The vaccine that they used was not similar to the current ones. Pasteur investigated how to weaken the virus without canceling it. He managed to extract an infected nerve tissue, which then gradually dried up to reduce its virulence.
This procedure, as unfamiliar as innovative, worked on dogs. He never tried people. The risk was completeThe child had no symptoms in the following days and weeks spent without complications. He survived against the entire forecastField
The success of the first case attracted patients from all over Europe and is forced to organize its own space
The result was a radical change. From this moment on Infected people began to arrive at Paris From different countries to receive treatment. The volume was such that Gracher organized a certain space for Visit them in the Ecolian Appendix Normal SpelNot far from the Pasteur laboratory. On October 20, 1885, just three months after the first treatment, the second case confirmed the potential of the method.
Jean-Baptist JupilThe 14 -year -old teenager was wounded by protecting a group of children from a frantic dog. The mayor of his city announced in the case of Pasteur, who decided to apply the vaccine. Jupil also survivedThe field after years, a sculpture was installed mainly the access of the Pasteur Institute. The image shows this in the full struggle with the animal, as a symbol of efforts to contain the disease.
The basis of the Pasteur Institute consolidated a new stage in the fight against viruses
The institute opened its doors in 1888. It was Graicher himself, who received the land and directed the construction. Inauguration Day, president of French Sadi Carno He went up to the title of the great officer of the legion of honor. He also corresponded to the original discourse. The essence, still active today, has become International link to the treatment of rage and other infectious diseasesField
The facts that marked the beginning of this story were collected by the Pasteur Institute. The official publication describes in detail that the first tests of a weakened virus began in 1880, and that after hundreds of unsuccessful attempts, a weak form of the virus was reached, which was achieved protected animals. The same document notes that “Joseph Meister was the first person to receive a vaccine developed from an artificially weakened microbe.”
None of the decisions made by the Pasteur and the Gracer proposed certainty. There were no previous clinical research, legal protection or favorable statistics. Only a hypothesis based on experiments with dogs and a child on the verge of death. Despite this, it worked.