dDuring the fantastic Paris 2024 Olympic and Paralympic Games, many doctors took advantage of the French enthusiasm for sport to talk about its benefits for physical and mental health. But few have discussed the crucial role of physical activity in preventing Alzheimer’s disease.
However, Alzheimer’s disease, a neurodegenerative disease that affects 1 million patients in France and millions of people around the world, represents a colossal challenge for public health in developed countries. With increasing life expectancy, this disease affects more and more people, raising the essential question of prevention. A question that is all the more burning since we still do not have effective treatments without serious side effects.
We remind you that the European health authorities (European Committee for Medicinal Products for Human Use, CMHP) did not authorize the marketing of Leqembi on the European market this summer. This product, registered in the United States, China, Hong Kong, Israel, Japan, Great Britain and South Korea, is unquestionably effective in reducing amyloid plaques, but the CMHP considered that the observed clinical benefit was not sufficient to justify the risks of the treatment. -related complications.
In any case, if preventive action is possible, it should in no case be neglected. However, one of the most promising prevention methods to delay the onset of this disease is physical activity.
But what really is the role of sport in the prevention of Alzheimer’s disease?
The challenge of Alzheimer’s disease
In France, 1 million people are affected and this number continues to increase. These alarming figures underline the urgency of finding solutions to prevent or slow the progression of this disease.
Alzheimer’s research has made considerable progress in recent decades, but its mechanism is complex and not yet fully understood. Only 1% of cases of Alzheimer’s disease are hereditary. Alzheimer’s disease is a multifactorial disease in which certain risk factors are modifiable and play an essential role in its appearance and development. According to researchers, 40% of cases of Alzheimer’s disease could be avoided with adequate prevention. And among the modifiable risk factors on which we can act, a sedentary lifestyle occupies an important place.
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